News

Sperm donor anonymity: a concept rendered obsolete by modern technology

The use of donor sperm began as a medical practice with a level of secrecy bordering on shame. In the United States, donor sperm insemination was first performed by Dr. William Pancoast in 1884 at Thomas Jefferson Medical College in Philadelphia. The patient was never told, and it is unclear whether the husband was completely informed as to exactly what was occurring. This was done to prevent “irreparable harm” to the resultant Continue reading…

Prevalence of ‘obesity-associated gonadal dysfunction’ in severely obese men and women and its resolution after bariatric surgery: a systematic review and meta-analysis

BACKGROUND Sexual dimorphism manifests noticeably in obesity-associated gonadal dysfunction. In women, obesity is associated with androgen excess disorders, mostly the polycystic ovary syndrome (PCOS), whereas androgen deficiency is frequently present in obese men in what has been termed as male obesity-associated secondary hypogonadism (MOSH). Obesity-associated gonadal dysfunction, consisting of PCOS in women and MOSH in men, is a frequent finding in patients with severe obesity and it may be ameliorated Continue reading…

Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential.

Older women tend to generate blastocyst-stage embryos with elevated levels of mitochondrial DNA, which is associated with aneuploidy and poor implantation, according to a new a new study of embryos derived from IVF clinics. The findings suggest that clinical tests to assess mitochondrial DNA levels could effectively help screen for “good” embryos during in vitro Continue reading…

The MicroRNA Signature of Mouse Spermatozoa Is Substantially Modified During Epididymal Maturation.

In recent years considerable effort has been devoted to understanding the epigenetic control of sperm development, leading to an increased appreciation of the importance of RNA interference pathways, and in particular miRNAs, as key regulators of spermatogenesis and epididymal maturation. It has also been shown that sperm are endowed with an impressive array of miRNA Continue reading…

Effect of paternal age on reproductive outcomes in oocyte donation model: a systematic review

Objective To perform a meta-analysis of the literature examining the influence of paternal age on oocyte donation outcomes. Design Systematic review of the literature with no language or time restrictions. Setting Not applicable. Patient(s) None. Intervention(s) None.  Main Outcome Measure(s) Pregnancy and live-birth rates. Result(s) By independent screening of titles and abstracts, two investigators selected original Continue reading…

Effect of metformin therapy and dietary supplements on semen parameters in hyperinsulinaemic males

Previous reports indicated that hyperinsulinaemic men may exhibit a higher percentage of poorly compacted DNA in their spermatozoa and less success in an IVF programme (Andrologia, 45, 2003, 18; Andrologia, 2014, doi: 10.1111/and.12227). The aim of this study was to investigate the effect of metformin (Glucophage®) and antioxidant treatment (StaminoGro®) on the semen parameters of Continue reading…

Onion and garlic extracts as potential antidotes for cadmium-induced biochemical alterations in prostate glands of rats

Cadmium (Cd) has been implicated in increased prostate gland malignancy risk in both wildlife and humans. This study examines the chemoprotective roles of onion and garlic extracts on Cd-induced biochemical alterations in the prostate glands of rats. Adult male Wistar rats were randomly divided into nine groups: control group received double distilled water; Cd group Continue reading…

Парафимоз у детей требует немедленного лечения!

Парафимоз у детей — неотложное состояние, при котором требуется немедленная врачебная помощь. Данное заболевание чаще всего возникает по причине фимоза — патологического сужения крайней плоти. При проведении гигиенических процедур у мальчиков может произойти ущемление головки пениса, что провоцирует нарушение кровообращения и лимфотока. Без своевременного врачебного вмешательства ребенку грозят серьезные осложнения! При парафимозе у детей лечение Continue reading…

2 в 1: коррекция искривления полового члена и обрезание

Кор­рек­ция ис­крив­ле­ния по­ло­во­го чле­на про­во­дит­ся с ис­поль­зо­ва­ни­ем раз­ных ме­то­дов. Один из них пред­по­ла­га­ет об­ре­за­ние край­ней пло­ти. Обыч­но дан­ные так­ти­ки ис­поль­зу­ют от­дель­но в силу раз­ных по­ка­за­ний. Сов­ме­щен­ная опе­ра­ция длит­ся дот 2,5 до 3 ча­сов. В первую оче­редь про­во­дят об­ре­за­ние край­ней пло­ти. В кли­ни­ке «Анд­ро­лог03» для этой цели воз­мож­но ис­поль­зо­ва­ние ра­дио­вол­но­во­го ап­па­ра­та «Сур­гит­рон». Он поз­во­ля­ет с ми­ни­маль­ны­ми по­ка­за­те­ля­ми ин­ва­зив­но­сти и кро­во­те­че­ния уда­лить лиш­нюю край­нюю плоть. Далее де­ла­ют Continue reading…